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Combination of gemcitabine and cisplatin in the treatment of patients with non-small-cell lung cancer
Author(s): 
Pages: 239-241
Year: Issue:  3
Journal: CHINA ONCOLOGY

Keyword:  肺肿瘤吉西他滨顺铂化疗;
Abstract: 目的:研究吉西他滨联合顺铂治疗非小细胞肺癌的疗效及毒性反应.方法:经病理组织学或细胞学证实的28例非小细胞肺癌患者给予吉西他滨 1 000 mg/m2静滴,第1、8、15天,顺铂80 mg/m2静滴,第1天,4周为1周期;或吉西他滨1 200 mg/m2,第1、8天,顺铂80 mg/m2静滴,第8天,3周为1周期.结果:可评价疗效28例,总效率53.6%(均为部分缓解).四周方案与三周方案有效率分别为58.3%和50.0%,两者差异无显著性.毒副反应主要为白细胞及血小板降低,但均可耐受.结论:吉西他滨联合顺铂治疗非小细胞肺癌具有较好的疗效,毒性可以耐受,不同用药方法疗效及毒副反应的差异值得进一步研究.
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