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Ondansetron plus dexamthasone in anti-emesis induced by cisplatin containing chemotherapy
Author(s): 
Pages: 257-258
Year: Issue:  3
Journal: CHINA ONCOLOGY

Keyword:  昂丹司琼化疗呕吐;
Abstract: 目的:研究国产品昂丹司琼(欧贝)加地塞米松防治顺铂化疗引起呕吐的疗效.方法:53例恶性肿瘤患者接受顺铂为主的化疗方案,顺铂用法,20 mg/m2,iv,第1~5天.昂丹司琼组:昂丹司琼 4 mg加地塞米松5 mg,1次/d,第1~5天;对照组:甲氧氯普胺10 mg加地塞米松5 mg,1次/d,第1~5天.结果:昂丹司琼组止吐率为82.6%,明显优于甲氧氯普胺组44.5%(P<0.01).结论:国产品昂丹司琼价格低,小剂量与地塞米松联合防治顺铂引起的呕吐,有良好的止呕效果,具有临床应用前景.
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