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Review on the genes involved in eyes morphogenesis in freshwater planarian
Author(s): 
Pages: 422-427
Year: Issue:  3
Journal: Acta Anatomica Sinica

Keyword:  EyeMorphogenesisGeneFreshwater planarian;
Abstract: Planarians are the earliest free-living platyhelminthes with triploblast and bilateral-symmetry and are the important animal group from water-inhabitation to land. They play an important role in studying the systematic evolution of animals. More importantly,planarians are the invertebrate model for the formation of the visual system,regeneration,evolution and development due to their simple eyes and powerful regenerative ability. In this paper,we summarize the genes involved in the regeneration of eyes of the planarian Dugesia japonica and their expression patterns and functional analysis during the differentiation of the eye precursor cells,optic nerve fiber growth,functional recovery of the visual system and the optic cup formation. We discusse some important questions which remain unclear in the eye regeneration and gave the prospects. Our provide some clues to the research on visual system of the higher animals.
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