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lei kang xin lv shi chang yao lin chuang gai kuang
Author(s): 
Pages: 343-346
Year: Issue:  6
Journal: World Clinical Drugs

Keyword:  异位搏动抗心律失常药物复极电生理特征索他洛尔普鲁卡因胺心脏猝死心肌细胞扭转型动作电位时程;
Abstract: <正> 抗颤动疗法与抗异位搏动疗法,在抗心律失常药物治疗中实际上是两个不同的概念。那些主要通过提高心肌电稳定和颤动电阈值,而防治室颤的药物,特称为抗颤动药,以Ⅲ类抗心律失常药胺碘酮为代表;通过抑制室性异位搏动,而纠治心律失常的药物,则被称为抗异位搏动药,以Ⅰ类的奎尼丁为代表。Ⅲ类抗心律失常药对预防心脏猝死、提高存活率有重要价值。Ⅲ类抗心律失常药的电生理特征是,延长心肌细胞动作电位时程,从而延长复极时
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