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zhi liao qian lie xian liu xin yao finasterid
Author(s): 
Pages: 252
Year: Issue:  4
Journal: World Clinical Drugs

Keyword:  前列腺瘤Finasterid还原酶抑制剂安慰剂有中;
Abstract: <正> Finasterid是5-α还原酶抑制剂,它竞争性地阻断5-a还原酶,这种酶使睾酮还原为原来的活性型二氢睾酮。给予单剂量本品后,二氢睾酮浓度迅速下降,而血浆中睾酮浓度不变。本品的疗效,在两次为期一年、以安慰剂为对照的双盲前瞻性研究中得到证实。这两次研究仍在进行,已临床1645例。在头一年临床中,有中度至严重症状的病人服用本品后,症状明显改善,前列腺缩小20~50%,排尿速度加快。对543例病人观察24个月,
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