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ba bi tu suan yan yu jie di zu zhi ji bing
Author(s): 
Pages: 253-254
Year: Issue:  4
Journal: World Clinical Drugs

Keyword:  结缔组织疾病纤维性海绵体炎掌挛缩病抗癫痫药巴比土酸盐扑痫酮苯妥英钠冻肩癫痛肩-手综合征;
Abstract: <正> 回顾性研究证明,掌挛缩病、冻肩(肩-手综合征)、Ledderhose综合征、纤维性海绵体炎(阴茎海绵体硬结)、纤维瘤、全身关节疼痛等的发生,与抗癫痫药治疗有关。作者前瞻性研究622例抗癫痫药(卡马西平、苯巴比妥、苯妥英钠和扑痫酮)治疗的患者。治疗6个月以上的406例中,共10例男性发生结缔组织疾病(掌挛缩病、冻肩、纤维性海绵体炎及/或其他关节疼痛),皆见于178例(6%)服用巴比土酸盐的患者,其中服用苯巴比妥的86例中6例、服用扑痫酮的92例中4例;服用卡马西平的107例、服用苯妥英钠的121例中,则无1例发生结缔组织疾
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