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lovastatin liao xiao he chang cheng bu liang fan ying
Author(s): 
Pages: 367
Year: Issue:  6
Journal: World Clinical Drugs

Keyword:  不良反应Lovastatin载脂蛋白病例发现肌病无症状横纹肌溶解VLDL降血脂药吉非罗齐;
Abstract: <正> 据200例治疗经验,Lovastatin 40mg每日2次,使血浆总胆固醇水平下降33%,甘油三酯下降24%,LDL胆固醇下降41%,VLDL胆固醇下降35%,HDL胆固醇增加9%,载脂蛋白AⅡ增加18%,LDL胆固醇/HDL胆固醇比例下降46%。Grundy指出,经Lovastatin治疗,冠心病危险性可下降50~60%,严重副作用极少见,本文作者综合1988年3月为止的4000个病例发现,本品严重不良反应为肌病(0.5%)和无症状的转氨酶增加(1.9%),停药后消失。
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