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kang qing guang yan yao aplonidine
Author(s): 
Pages: 363-364
Year: Issue:  6
Journal: World Clinical Drugs

Keyword:  抗青光眼药Aplonidine大鼠主动脉眼内压肾上腺素能受体激动剂眼房水咪唑啉药理作用小梁;
Abstract: <正> 异名 Iopidine 化学名 2-(4-氨基-2,6-二氯苯基亚胺基)咪唑啉盐酸盐药效分类青光眼药开发单位 (美国)Alcon Lab Inc 上市厂商 (美国)Alcon Lab Inc 药理作用本品通过激活眼内α2肾上腺素能受体降低眼内压(IOP),推测是药物降低了眼房水形成的结果。尽管许多文章已经提到本品是α2肾上腺素能激动剂,但它似乎还有强烈的α1激动剂活性,至少在某些系统是这样。对大鼠主动脉突触后受体的激动作用非常强烈,但所涉
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