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ace yi zhi ji lei mi pu li (ramipril) mei ri 1 ci de shou ji xiao ying he 24 xiao shi de jiang ya xiao guo
Author(s): 
Pages: 366
Year: Issue:  6
Journal: World Clinical Drugs

Keyword:  雷米普利ACE抑制剂Ramipril首剂效应原发性高血压作用时间纳普血管紧张素抗高血压作用动物实验;
Abstract: <正> 第一个ACE抑制剂卡托普利(Captopril)降压效果显著,但作用时间较短。随后发展的依纳普利(Enalapril)克服了前述缺点,是一个有效的降压药。雷米普利(Ramipril)经动物实验证明比依纳普利起效更快,作用时间更长;健康人服药后1小时ACE活性开始下降,5mg能完全抑制ACE达8小时,残余效应长达8天;高血压患者口服本品后可见血压明显下降,持续24小时。 12例原发性高血压患者口服雷米普利首剂10mg,1小时后收缩压开始下降,5小
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