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yao wu dui zhi fang xing shuan ji wu li wen ding xing de ying xiang
Author(s): 
Pages: 48-51
Year: Issue:  6
Journal: World Clinical Drugs

Keyword:  物理稳定性晶型半合成多晶型现象浓度场差示热分析处方研究生物利用度扑热息痛转化速度;
Abstract: <正> 已经证明半合成的脂肪栓基质在贮藏期中,其晶型由非稳定性A型逐步转化成比较稳定的B型。随之制剂发生性质改变,如熔点增加,软化时间延长,药物释放减少等等。由于栓剂中含有各种理化性质和各种浓度的药物,而药物与基质间会发生一定程度的作用,所以有必要阐明药物对栓剂性质的影响。
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