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zuo jia bing fu suan zai shui rong ye zhong de wen ding xing
Author(s): 
Pages: 62
Year: Issue:  6
Journal: World Clinical Drugs

Keyword:  巯甲丙脯酸金属螯合剂原发性高血压金属化合物酰胺基反应速度常数分解速度氧化分解抗氧化剂一级反应;
Abstract: <正> 巯甲丙脯酸(Captopril)是一种口服的降压药,经抑制血管紧张素转化酶而起作用。该药副作用少,降压效果确切,特别是原发性高血压患者的良药。目前它已有片剂上市,也可能希望以糖浆、注射剂形式给药。本文就巯甲丙脯酸在水溶液中的稳定性进行讨论。巯甲丙脯酸含有巯基,易发生氧化,其酰胺基又易水解。金属化合物可促进氧化,而EDTA等金属螯合剂则可抑制氧化。将巯甲丙脯酸水溶液5mg/ml装入小瓶
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