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wu ling jiao nang lian he she qu lin zhi liao pa jin sen bing he bing yi yu zhuang tai de liao xiao guan cha
Author(s): 
Pages: 199-200,216
Year: Issue:  3
Journal: Zhejiang Practical Medicine

Keyword:  乌灵胶囊舍曲林帕金森抑郁状态;
Abstract: 目的:观察乌灵胶囊联合舍曲林治疗帕金森病合并抑郁状态的临床疗效。方法将60例帕金森病合并抑郁状态患者随机分为治疗组和对照组各30例,对照组采用常规帕金森治病治疗和舍曲林治疗,治疗组在此基础上加用乌灵胶囊治疗,治疗8周后比较两组的有效率,并用帕金森病统一评分量表(UPDRS)评价帕金森病症状改善情况,用汉密顿抑郁量表(HAMD)17项评价抑郁状态的改善情况。结果治疗8周后治疗组总有效率高于对照组(P<0.05);治疗后4周和8周,与对照组比较UPDRS功能量表及HAMD量表评分均有显著下降(均P<0.05),对照组治疗4周后UPDRS功能量表及HAMD量表评分均低于治疗前(均P<0.05),而治疗组仅用2周即起效;加用乌灵胶囊未发生严重不良反应。结论乌灵胶囊联合舍曲林较单独用舍曲林治疗帕金森病合并抑郁状态起效快、总有效率高,且未出现严重的不良反应。
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