Analysis of drug resistance of Neisseria gonorrhoeae
Author(s): MA Jianfei, LI Gang, ZHANG Yinv
Pages: 70-72
Year: 2015 Issue: 6
Journal: The Chinese Journal of Human Sexuality
Keyword: Gonorrhea; Neisseria gonorrhoeae; Infection; Resistance analysis;
Abstract: Objectives:To analyze the Neisseria gonorrhoeae resistance of gonorrhea among 228 patients. Methods:Disk diffusion method (KB method)was used to detect Neisseria gonorrhoeae.The nitrocefin paper method was used to detect β-lactamase.Results:Among the 228 Neisseria gonorrhoeae,there were 72 from Ning-hai County Chinese Medicine Hospital,among which 19 positive β-lactamase were tested;156 Neisseria gonor-rhoeae were from Huzhou City,MCH,among which 41 positive β-lactamase were tested.Positive detection rate in 228 strains accounted for 26.32%.The resistance of all strains for Neisseria gonorrhoeae to five kinds of antibacteri-al drugs had significant difference.Resistance to tetracycline,penicillin and ciprofloxacin resistance was relatively high and resistance to ceftriaxone,spectinomycin was relatively low.Conclusion:According to research data,tetra-cycline,penicillin and other drugs should be avoided as the preferred antibacterial drugs in clinic,while ceftriaxone and spectinomycin should be properly selected as the first drug choice for the treatment of Neisseria gonorrhoeae in-fection in clinic.
Pages: 70-72
Year: 2015 Issue: 6
Journal: The Chinese Journal of Human Sexuality
Keyword: Gonorrhea; Neisseria gonorrhoeae; Infection; Resistance analysis;
Abstract: Objectives:To analyze the Neisseria gonorrhoeae resistance of gonorrhea among 228 patients. Methods:Disk diffusion method (KB method)was used to detect Neisseria gonorrhoeae.The nitrocefin paper method was used to detect β-lactamase.Results:Among the 228 Neisseria gonorrhoeae,there were 72 from Ning-hai County Chinese Medicine Hospital,among which 19 positive β-lactamase were tested;156 Neisseria gonor-rhoeae were from Huzhou City,MCH,among which 41 positive β-lactamase were tested.Positive detection rate in 228 strains accounted for 26.32%.The resistance of all strains for Neisseria gonorrhoeae to five kinds of antibacteri-al drugs had significant difference.Resistance to tetracycline,penicillin and ciprofloxacin resistance was relatively high and resistance to ceftriaxone,spectinomycin was relatively low.Conclusion:According to research data,tetra-cycline,penicillin and other drugs should be avoided as the preferred antibacterial drugs in clinic,while ceftriaxone and spectinomycin should be properly selected as the first drug choice for the treatment of Neisseria gonorrhoeae in-fection in clinic.
Related Articles