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Study on diagnose and significance of hepatic fibrosis histological stage by examing the levels of serum makers
Author(s): 
Pages: 4-6
Year: Issue:  2
Journal: JOURNAL OF HENAN UNIVERSITY (MEDICAL SCIENCE)

Keyword:  肝脏炎症纤维化分期血清学指标;
Abstract: 目的:探讨慢性乙型肝炎、肝纤维化血清指标与肝组织学改变程度的关系.方法:选择慢性乙型肝炎患者(LHB),在检测患者血清透明质酸(HA)、Ⅲ型前胶原(PCⅢ)、板层素(LN)、前胶原Ⅳ(Ⅳ-C)、转化生长因子β1(TGF-β1)同时行肝活检,对肝组织进行病理炎症、纤维化分期.结果:随着分级、分期的上升,该5项指标均有不同程度的上升,PCⅢ与炎症关系密切.HA、TGF-β1与纤维化关系密切.结论:通过肝纤维化5项指标联合检测.综合分析可估计肝内炎症及纤维化程度.
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