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miao yao tong feng ting tang dui ji xing tong feng xing guan jie yan sd mo xing da shu guan jie hua mo cox-2 biao da de ying xiang
Pages: 27-29
Year: Issue:  4
Journal: Asia-Pacific Traditional Medicine

Keyword:  痛风痛风停汤民族药COX-2;
Abstract: 目的:观察苗药痛风停汤对SD模型大鼠COX-2的影响。方法:将48只雄性SD大鼠随机分为四组各12只:空白组(A组)、模型组(B组)、痛风停汤组(C组)及双氯芬酸钠对照组(D组),制备SD模型大鼠,RT-PCR检测COX-2(环氧化酶-2)的含量。结果:痛风停汤组与模型组比较,COX-2的表达明显下降(P<0.05),痛风停汤组与双氯芬酸钠组比较,COX-2的表达有不同程度的改善,但两组总体疗效比较无显著差异(P>0.05)。结论:痛风停汤能抑制急性痛风性关节炎SD模型大鼠C0X-2的表达。
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