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Value of application of Auditory cognitive potential P300 in diagnosis of multiple cerebral infarction dementia
Author(s): XIE Bing, CHEN Ying
Pages: 200-
202
Year: 2002
Issue:
2
Journal: JOURNAL OF TIANJIN MEDICAL UNIVERSITY
Keyword: 多发脑梗塞性痴呆; 简易智能状态量表; 事件相关电位P300;
Abstract: 目的:探讨多发脑梗塞性痴呆(MCID)听觉认知电位P300变化特点及诊断价值.方法:用简易智能状态量表(MMSE)、临床痴呆评定量表(CDR)和听觉P300检测MCID,多发性脑梗塞(MCI)和正常对照组(NC).结果:MCID组与MCI和NC组比较MMSE评分明显降低,P300潜伏期明显延长,均有统计学意义(P<0.01).轻度痴呆者P300波幅正常,重者P300波幅明显降低(P<0.05).MCID组P300潜伏期与MMSE评分呈显著性负相关(P<0 005).结论:P300检查更利于MCID的诊断和疾病严重程度的观察.
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