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Clinical study of CK-20mRNA gene expression in peripheral blood of patient with cardic carcinoma
Author(s): 
Pages: 131-132
Year: Issue:  2
Journal: JOURNAL OF TAISHAN MEDICAL COLLEGE

Keyword:  贲门癌RT-PCRCK-20mRNA外周血;
Abstract: 目的探讨贲门癌早期转移的生物标记物CK-20mRNA基因表达及其临床意义.方法应用巢式逆转录多聚酶链反应(RT-PCR)法检测29例贲门癌患者外周血CK-20mRNA的表达情况.结果 29例贲门癌患者中12例外周血CK-20mRNA表达阳性,按UICC国际TNM标准分期外周血CK-20mRNA的表达率分别为:Ⅰ期0/5,Ⅱ期2/10,Ⅲ期8/12,Ⅳ期2/2.结论贲门癌患者外周血CK-20mRNA阳性表达可作为贲门癌血行转移的分子指标之一,与TNM分期有一定关系.
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