Necroptosis and Cerebral ischemia
Author(s): Zhu Xinyong, Lu Zhiw ei, Xu En
Pages: 139-144
Year: 2015 Issue: 2
Journal: International Journal of Cerebrovascular Diseases
Keyword: Apoptosis; Necrosis; CelDeath; BrainIschemia;
Abstract: Necroptosisisanewlydiscoveredwayofceldeath.Itisassociatedwithinfection, tumor, heart disease, neurodegenerative disease, cerebrovascular disease, and other diseases. Necroptosis involves in the occurrence and development of cerebral ischemia-reperfusion injury. Therefore, w hen the cerebral ischemia is studied in depth, the induction, regulation and blocking mechanisms of necroptosis are not only conducive to deepen the understanding of the death mode of brain cel s, but also conducive to develop new drugs for the new targets in the treatment of cerebral ischemia.
Pages: 139-144
Year: 2015 Issue: 2
Journal: International Journal of Cerebrovascular Diseases
Keyword: Apoptosis; Necrosis; CelDeath; BrainIschemia;
Abstract: Necroptosisisanewlydiscoveredwayofceldeath.Itisassociatedwithinfection, tumor, heart disease, neurodegenerative disease, cerebrovascular disease, and other diseases. Necroptosis involves in the occurrence and development of cerebral ischemia-reperfusion injury. Therefore, w hen the cerebral ischemia is studied in depth, the induction, regulation and blocking mechanisms of necroptosis are not only conducive to deepen the understanding of the death mode of brain cel s, but also conducive to develop new drugs for the new targets in the treatment of cerebral ischemia.
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