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Clinical and pathological feature and prognosis for multilocular cystic renal cell carcinoma
Author(s): 
Pages: 188-191
Year: Issue:  3
Journal: Chinese Journal of Urology

Keyword:  Multilocular cystic renal cell carcinomaClinicopathological featuresPrognosis;
Abstract: Objective To investigate the clinicopathological features of multilocular cystic renal cell carcinoma (MCRCC).Methods The clinicopathological data of 27 patients with MCRCC diagnosed and treated in Fudan University Shanghai Cancer Center from 2002 to 2012 were retrospectively analyzed.There were 19 males and 8 females with non-specific clinical manifestation.CT scan showed a polycystic mass with enhanced cystic wall and septum in enhancement scanning.Of which,21 cases of Bosniak Ⅲ and 6 cases of Bosniak Ⅳ.MRI revealed a mass with long T1 and T2 signal with clearly separated-liked enhanced mass in enhancement scan.Ten cases of tumor located in the left renal,16 cases in the right renal,1 case in the double kidney.The mean of tumor diameter was 4.4 (1.0-8.0) cm.Eleven patients underwent radical nephrectomy while the other 16 cases received nephron sparing surgery.Results The pathological staging showed pT1aN0M0 in 19 cases,pT1bN0M0 in 6 cases,and pT2N0M02 cases.In immunohistochemical study,tumor cells from 18 cases were positive for CD10,17 positive for vimentin,27 positive for EMA,20 positive for CK7,while all negative for CD68.During 5-145 months of follow-up,none of patients showed any evidence of recurrence and metastasis,with non-tumor-related mortality.Conclusions MCRCC as a rare type of kidney cancer has low pathological stage and good prognosis,and should be treated with surgery if the diagnosis of MCRCC is suspected and confirmed.
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