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Early Effect Following the Resection of Ileal-Cecum and Right HemicolonAn Experimental Study
Author(s): XIANG Bo, WEI Fukang, LUO Qicheng, LIU Min, LIU Juxian
Pages: 96-
99
Year: 2002
Issue:
2
Journal: CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY
Keyword: 回盲部; 结肠; 手术;
Abstract: 目的 探讨回盲部和右半结肠切除后早期对机体的影响.方法 20只仔猪随机均分为两组.手术组切除末端回肠50 cm、盲肠及近端结肠50 cm,回-结肠端端吻合; 对照组正常喂养6周.检测两组间多项指标的变化. 结果①两组间身长差异无显著性意义(P>0.05),术后3 w起手术组体重较对照组明显降低(P<0.05); ②手术组回肠需氧细菌数由术前104~107个/ml增加到术后6 w时的109~1011个/ml(P<0.05); ③手术组血清胆汁酸由术前(17.1±4.2) mmol/L下降至术后3 w(9.2±2.2) mmol/L,术后6 w(8.44±0.98) mmol/L(P<0.05); ④手术组术后4 w内均排稀溏样粪便,6 w后逐渐恢复正常; ⑤血清Vit B12无显著性改变(P>0.05),未出现巨幼红细胞性贫血; ⑥肝功指标、血清K+、Na+、Cl-均无显著性改变(P>0.05).结论回盲部和右半结肠切除后早期将导致"回肠细菌结肠化现象"; 干扰水分吸收而导致粪便变稀; 影响胆汁酸的肠-肝循环; 出现消瘦倾向.但肝功各项指标、血清Vit B12、K+、Na+、Cl-等,短期内无显著性影响.临床中此段肠道应尽可能保留或切除后重建回盲瓣功能.
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