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Local Intra-arterial thrombolysis for treatment of acute cerebral infarction
Author(s): 
Pages: 100-103
Year: Issue:  2
Journal: CHINESE JOURNAL OF GERIATRIC CARDIOVASCULAR AND CEREBROVASCULAR DISEASES

Keyword:  脑梗塞溶栓治疗尿激酶;
Abstract: 目的研究经血管内选择性溶栓治疗49例8 h内发病的急性脑梗死患者,以评估动脉内溶栓治疗急性脑梗死的疗效.方法患者均急诊行头颅CT检查,31例经股动脉插管,全脑血管造影确认脑梗死,再选择性将导管插入患侧颈内动脉和椎动脉并注入尿激酶50~75万单位行接触性和区域性溶栓治疗.对照组18例行常规治疗.结果溶栓后血管再通率为71%,有效率为83%.23例颈内动脉系和4例椎基动脉系梗死在溶栓后2周内神经损害体征明显改善.2例死亡.溶栓组改良爱丁堡-斯堪的纳维亚脑卒中量表(MESSS)评分改善(21.6±13.6)分;对照组改善(5.9±5.3)分.溶栓组发病时间越短其疗效越好.结论选择性动脉内溶栓治疗是一种治疗急性脑梗死的有效方法,具有较高的血管再通率.
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