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Issue:
Telomere and telomerase
Author(s):
LI Jiping
,
REN Xueping
Pages:
67
-
69
Year:
2002
Issue:
2
Journal:
JOURNAL OF ZHOUKOU TEACHERS COLLEGE
Keyword:
端粒
;
端粒酶
;
衰老
;
癌变
;
Abstract:
端粒和端粒酶是近年来生命科学研究的热点问题之一.端粒是染色体末端独特的蛋白质-DNA结构,在保护染色体的完整性和维持细胞的复制能力方面起着重要的作用.端粒酶则是由RNA和蛋白质亚基组成的,能够延长端粒的一种特殊反转录酶.端粒长度和端粒酶活性的变化与细胞衰老和癌变密切相关.
Citations
TRF2 protects human telomeres from end-to-end fusion
van Steensel B
Cell
Telomere shortening and tumor-formation by mouse cells lacking telomerase RNA
Blasco M A
Cell
Mutational analysis of tetrahymena telomerase RNA:identification of residues affection teoolomerase activity in vitro
Autexier C
Nucleic Acids Research
Reversetransciptase motifs in the catalytic subunit of telomerase
Linger J Hughes T R
SCIENCE
端粒及端粒酶的研究进展
任建国
生物化学与生物物理进展
端粒、端粒酶与细胞凋亡
文军
国外医学(生理、病理科学与临床分册)
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