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Changes of Plasma BNP and Cys-C Level and Cardiac Function in Elderly Patients with Chronic Congestive Heart Failure
Pages: 169-171
Year: Issue:  2
Journal: Research of Traditional Chinese Medicine

Keyword:  Key wods:chronic congestive heart failureelderly patientsbrain natriuretic peptidecystatin Ccardiac function;
Abstract: Objective To observe the changes of plasma brain natriuretic peptide(BNP),cystatin C(Cys-C)levels and cardiac function in elderly patients with chronic congestive heart failure(CHF).Methods Sixty-three elderly patients with CHF were choosed randomly,and divided into 4 groups according to the New York Heart Association(NYHA)functional classification:13in group I,16 in group II,19 in group III and 15 in group IV.The changes of plasma BNP and Cys-C,left ventricular end diastolic diameter(LVD),left ventricular end systolic diameter(LVS),ejection fraction(EF)and cardiac output(CO)were observed.Results With the changing of cardiac function,the levels of plasma BNP,Cys-C,LVD and LVS were increased obviously while LVEF and CO were decreased.That meant the worse cardiac function,the higher plasma BNP and Cys-C level,which was of statistical significance(P <0.05).Conclusion Plasma BNP and Cys-C levels and cardiac function are closely related to cardiac function in elderly patients with CHF,which can be used as sensitive index of the evaluation of cardiac function,treatment effect and prognosis.
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