The clinical application of magnifying endoscopy with narrow-band imaging(ME-NBI) in targeted-biopsy of intestinal metaplasla
Author(s): QIU Quanxing, TANG Zuo, HU Xuejun, YAO Ping
Pages: 344-345,346
Year: 2015 Issue: 2
Journal: Anhui Medical and Pharmaceutical Journal
Keyword: narrow band imaging; gastric mucosa; Intestinal metaplasla;
Abstract: Objective To investigate the morphologic features of gastric intestinal metaplasia (IM) using magnifying endoscopy with narrow-band imaging( ME-NBI) and its clinical use in the diagnosis of IM under ME-NBI targeted biopsy.Methods The endoscopic examination was performed on 50 patients and suspected lesions of gastric body associated with IM were further observed by ME-NBI. The biopsy specimens were obtained from regions containing light blue crest ( LBC) ,marginal turbid band ( MTB ) mucosa or normal area for pathological examination, and the results were analyzed.Results In 50 patients examined with ME-NBI, we received 112 pieces of biopsy samples.IM was pathologically confirmed in patients.For the diagnosis of IM,MTB had a sensitivity and specificity of 97.1%and 52.3%,respectively,and the corresponding values for LBC were 31.4%and 95.2%.When groups classified according to the presence or absence of MTB and LBC were compared,severe IM was more commonly seen in MTB+/LBC+areas than in the other two regions.Conclusion It has been demonstrated that NBI–ME can improve the diagnosis of IM by targeted-biopsy in LBC or MTB region,which is helpful in early diagnosis of gastric cancer.
Pages: 344-345,346
Year: 2015 Issue: 2
Journal: Anhui Medical and Pharmaceutical Journal
Keyword: narrow band imaging; gastric mucosa; Intestinal metaplasla;
Abstract: Objective To investigate the morphologic features of gastric intestinal metaplasia (IM) using magnifying endoscopy with narrow-band imaging( ME-NBI) and its clinical use in the diagnosis of IM under ME-NBI targeted biopsy.Methods The endoscopic examination was performed on 50 patients and suspected lesions of gastric body associated with IM were further observed by ME-NBI. The biopsy specimens were obtained from regions containing light blue crest ( LBC) ,marginal turbid band ( MTB ) mucosa or normal area for pathological examination, and the results were analyzed.Results In 50 patients examined with ME-NBI, we received 112 pieces of biopsy samples.IM was pathologically confirmed in patients.For the diagnosis of IM,MTB had a sensitivity and specificity of 97.1%and 52.3%,respectively,and the corresponding values for LBC were 31.4%and 95.2%.When groups classified according to the presence or absence of MTB and LBC were compared,severe IM was more commonly seen in MTB+/LBC+areas than in the other two regions.Conclusion It has been demonstrated that NBI–ME can improve the diagnosis of IM by targeted-biopsy in LBC or MTB region,which is helpful in early diagnosis of gastric cancer.
Related Articles