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Analysis on distribution and drug resistance of pathogens in First Affiliated Hospital of Chengdu Medical College in 2013
Author(s): 
Pages: 212-216
Year: Issue:  2
Journal: World Phytomedicines

Keyword:  pathogendrug resistanceGram-negative bacteriamicrobial sensitivity tests;
Abstract: Objective To investigate distribution and drug resistance of pathogens in the First Affiliated Hospital of Chengdu Medical College in 2013, and to provide the basis for the clinical rational use of antibiotics. Methods The clinical data of pathogens in the First Affiliated Hospital of Chengdu Medical College in 2013 were reviewed retrospectively. Results Totally 3 805 strains of pathogens were isolated, including 2 484 strains(65.3%) of Gram-negative bacilli among which Escherichia coli, Enterobacter cloacae, Pseudomonas aeruginosa, and Klebsiella pneumoniae pneumoniae were dominant; 928 strains(24.4%) of Gram-positive bacilli among which Staphylococcus aureus were dominant; 393 strains(10.3%) of fungi among which Candida albicans was dominant. Drug sensitivity test showed that Gram-negative bacilli including E. coli, P. aeruginosa, and K. pneumoniae pneumoniae were sensitive to carbapenems, penicillin, and cephalosporins/β-lactamaseinhibitors. While E. cloacae had higher resistance, only was sensitive to polymyxin E. Gram-positive bacilli were sensitive to vancomycin, while were resistant to macrolides such as erythromycin, and penicillin. C. albicans was sensitive to 5-fluorocytosine, fluconazole, voriconazole, amphotericin B, and itraconazole. Conclusion It is necessary to statistically analyze the distribution and drug resistance of pathogens periodically, so as to provide the basis for clinicians reasonably using antibiotics. Thus, it can improve the cure rate of infection and delay the generation of antibiotic resistant bacteria.
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