Clinic significance of finasteride in treatment of postoperative bleeding TURP surgery of benign prostatic hyperplasia
Author(s): Guo Qilin, Luo Zhigang, Qiyang People′s Hospital, The Second Affiliated Hospital of South China
Pages: 182-183+186
Year: 2015 Issue: 2
Journal: Modern Medicine & Health
Keyword: Transurethral resection of the prostate; Blood loss; surgical; Bleeding; Prostatic hyperplasia/surgery; Administration; oral; Finasteride;
Abstract: Objective To approach the clinical significance of the intraoperative and postoperative bleeding the short-term oral finasteride in the TURP method. Methods A retrospective study of 86 patients with benign prostatic hyperplasia of TURP in Qiyang People′s Hospital from June 2012 to September 2013 were divided into group A(46 cases) with 5 mg oral finasteride one week before surgery and group B(40 cases) without oral finasteride. The intraoperative and postoperative blood loss,electric cut operation time,postoperative maximum urinary flow rate measurement of every patients were recorded. Results There was no statistical significance between group A and group B before the operation in prostate volume,maximum uroflow rate(P>0.05)[(43.7±12.6),(45.2±8.9)m L vs(7.2±5.6),(7.3±3.6)m L/s]. The maximum uroflow rate of group A was(15.7±7.8)m L/s while group B being(14.8±9.2)m L/s. The difference had no statistical significance between the two group(P>0.05). There was no statistical significance between group A and group B in maximum uroflow(P>0.05). Compared the operation time [(46.0±15.1),(57.6±17.2)min],the intraoperative bleeding [(154.7±78.9),(226.0±94.5)m L],the postoperation bleeding [(89.2±42.3),(112.0±87.6)m L] between the two groups,it had statistical significance in difference(P<0.05). Conclusion Preoperative short-term use regular doses of finasteride could significantly reduce the intraoperative and postoperative bleeding and shorten the operation time.
Pages: 182-183+186
Year: 2015 Issue: 2
Journal: Modern Medicine & Health
Keyword: Transurethral resection of the prostate; Blood loss; surgical; Bleeding; Prostatic hyperplasia/surgery; Administration; oral; Finasteride;
Abstract: Objective To approach the clinical significance of the intraoperative and postoperative bleeding the short-term oral finasteride in the TURP method. Methods A retrospective study of 86 patients with benign prostatic hyperplasia of TURP in Qiyang People′s Hospital from June 2012 to September 2013 were divided into group A(46 cases) with 5 mg oral finasteride one week before surgery and group B(40 cases) without oral finasteride. The intraoperative and postoperative blood loss,electric cut operation time,postoperative maximum urinary flow rate measurement of every patients were recorded. Results There was no statistical significance between group A and group B before the operation in prostate volume,maximum uroflow rate(P>0.05)[(43.7±12.6),(45.2±8.9)m L vs(7.2±5.6),(7.3±3.6)m L/s]. The maximum uroflow rate of group A was(15.7±7.8)m L/s while group B being(14.8±9.2)m L/s. The difference had no statistical significance between the two group(P>0.05). There was no statistical significance between group A and group B in maximum uroflow(P>0.05). Compared the operation time [(46.0±15.1),(57.6±17.2)min],the intraoperative bleeding [(154.7±78.9),(226.0±94.5)m L],the postoperation bleeding [(89.2±42.3),(112.0±87.6)m L] between the two groups,it had statistical significance in difference(P<0.05). Conclusion Preoperative short-term use regular doses of finasteride could significantly reduce the intraoperative and postoperative bleeding and shorten the operation time.
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