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Relationship between autophagy and thyroid cancer
Author(s): Li Xingjia, Cao Meng, Liu Chao
Pages: 56-
58
Year: 2015
Issue:
1
Journal: International JOurnal of Endocrinology and Metabolism
Keyword: Thyroid cancer; Autophagy; Therapy;
Abstract: Thyroid cancer is the most common malignancy in endocrine system,although it has a good prognosis,some thyroid cancer may become resistant to radiotherapy and chemotherapy via apoptosis escaping.Autophagy,as a mechanism for cell response to environmental stress,has a natural link with various diseases.Cell homeostasis which is maintained by foundational autophagy may be broken by changes of autophagy level,and this will directly or indirectly participate in the pathogenesis and progression of multiple cancers including thyroid cancer.For those radiotherapy and chemotherapy resistance cancers,autophagy may become a new therapeutic target.Therefore,studying the relationship between autophagy and thyroid cancer is important for the treatment of thyroid cancer.
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