Author(s): YU Shuang, BO Yu-long, XU Yong-mei, SHI Wei-dong, ZHOU Wan-hua, Department of anesthesiology of the second affiliated hospital of Harbin medical university
Pages: 198-200
Year: 2015 Issue:  1
Journal: Biomagnetism
Keyword:  Sevoflurane; Diabetes mellitus; Ischemia/reperfusion injury;
Abstract: Diabetes Mellitus(DM) is a frequently-occurring disease. It’s seriously threatening people’s health. And it is one of the important factors to coronary heart disease. Myocardial ischemia / reperfusion(I/R) injury is a common pathological process, and how to reduce I/R injury has been one of the international hot points. DM and I/R injury both hurt heart function, and related research demonstrates that DM can enhance myocardial I/R injury. Studies show that ischemia preconditioning(IPC) can release myocardial I/R injury,and anesthetic induced-preconditioning(APC) has the same protective effect as IPC. Sevoflurane is one more common inhalational anesthetic, and has protective effect on myocardial I/R injury, too. This paper is about the influence and mechanism of sevoflurane to diabetes myocardial ischemia/reperfusion injury.