Author(s): LIU Jun-feng, XING Juan, LI Xiang-min, QIN Dan, LI Jin-lian, Municipal Hospital of Bincheng District of Binzhou City, The Medical Physics Laboratory of Bin Zhou Medical College, The Fuctional Physiology Laboratory of Bin Zhou Medical College
Pages: 576-580
Year: 2015 Issue:  3
Journal: Biomagnetism
Keyword:  Magnetic nanoparticles; Hepatoma cells; Biological effect;
Abstract: Magnetic nanoparticle is a kind of intelligent nano material. It is widely used in biomedical fields because of its unique properties. A large number of experimental research have been done in the treatment of liver cancer. Exploring the new ways of magnetic nanoparticles in liver cancer treatment has great practical significance. This article summarizes the current research state and progress of magnetic nanoparticles in hepatoma cells biology and reviews them from three aspects: Directly acting on the liver cancer cells,the biocompatibility,distribution and biological effects in liver cancer cells of magnetic nanoparticles are explored; Magnetic nanoparticles and external magnetic field(static magnetic field,SMF,extremely low frequency alternating magnetic field and high-frequency alternating magnetic field,EMF) synergistically act on hepatoma cells; Plus modified magnetic nanoparticles(magnetic albumin nanoparticles,nano-magnetic fluid,magnetic liposomes,etc.) act on hepatoma cells as drug carriers.