Research progress of HIF-1 in cancers
Author(s): ZHANG Bo, ZHAO Gang
Pages: 565-568
Year: 2014 Issue: 6
Journal: Journal of Practical Oncology
Keyword: Hypoxia; HIF-1; Neoplasms;
Abstract: Transcription factorhypoxia inducible factor -1(HIF-1)plays a key role in cell adaption to hypoxia(from 21%O2 to 1%O2).Researches have shown that HIF -1 is closely related to occurrence and de-velopment in many malignant cancers .In this paper,we review the effect of HIF -1 in tumor growth,metastasis, apoptosis and angiogenesis .
Pages: 565-568
Year: 2014 Issue: 6
Journal: Journal of Practical Oncology
Keyword: Hypoxia; HIF-1; Neoplasms;
Abstract: Transcription factorhypoxia inducible factor -1(HIF-1)plays a key role in cell adaption to hypoxia(from 21%O2 to 1%O2).Researches have shown that HIF -1 is closely related to occurrence and de-velopment in many malignant cancers .In this paper,we review the effect of HIF -1 in tumor growth,metastasis, apoptosis and angiogenesis .
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