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Research Progress on Gastroesophageal Reflux Disease during Pregnancy
Author(s): 
Pages: 757-759
Year: Issue:  12
Journal: Chinese Journal of Gastroenterology

Keyword:  Gastroesophageal Reflux DiseasePregnancyTherapy;
Abstract: Gastroesophageal reflux disease( GERD)is a common gastrointestinal disorder during pregnancy. Several factors including decreased lower esophageal sphincter pressure, increased intra-abdominal pressure secondary to the enlarged gravid uterus and alteration in gastrointestinal motility have been linked to the pathogenesis of GERD. Diagnosis and treatment of diseases during pregnancy are unique. Life-style modifications are helpful for the majority of patients. When considering medical therapy,a step-up therapy from antacids,H2 receptor antagonists to proton pump inhibitors should be followed. In patients without a prior history of reflux,symptoms usually are relieved after delivery.
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