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li xi bao ji luo ci ji yin zi zai que xue xing nao zu zhong zhong de nao bao hu zuo yong yan jiu jin zhan
Author(s): 
Pages: 1557-1559
Year: Issue:  12
Journal: Research of Traditional Chinese Medicine

Keyword:  缺血性脑卒中粒细胞集落刺激因子神经保护;
Abstract: 粒细胞集落刺激因子(G-CSF)是造血生长因子,主要用于各种原因引起的中性粒细胞减少症、骨髓移植等。近年来已有研究在动物实验中证实了G-CSF可缩小脑缺血再灌注动物模型的脑梗死体积,改善功能预后,其作用机制可能包括抗凋亡、抗炎症、促进神经和血管发生、诱导神经分化等。本文主要对G-CSF的信号传导途径及神经保护作用机制进行综述。
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