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LASS family and tumor
Author(s): Xiong Tao, Wang Haifeng, Wang Jiansong
Pages: 734-
736
Year: 2014
Issue:
10
Journal: Journal of International Oncology
Keyword: Ceramides; Genes; tumor suppressor; Neoplastic process;
Abstract: LASS gene family is a group of highly conserved and longevous gene LASS protein has a ceramide synthase activity,which can synthesize different types of ceramides.Ceramide is a key intermediate in tumor cells growth,signal transduction and other aspects.Thus it is inferred that the expression of LASS gene can suppress the occurrence and development of tumor within a certain range.
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