Author(s): FU Min, WU Wei, TANG Luo-Sheng, LU Xiao-He, Department of Ophthalmology, Zhujiang Hospital of Southern Medical University, Department of Ophthalmology, the Second Affiliated Hospital of Central South University
Pages: 1038-1041
Year: 2014 Issue:  11
Journal: Recent Advances in Ophthalmology
Keyword:  diabetic retinopathy; vitreoretinal interface; posterior vitreous detachment; panretinal photocoagulation; optical coherence tomography;
Abstract: Objective To observe and compare the changes of vitreoretinal interface in patients with proliferative diabetic retinopathy( PDR) before and after panretinal photocoagulation( PRP). Methods A total of 217 eyes of 132 patients with non-insulin dependent diabetes were divided into 4 groups: no DR group,light and moderate NPDR group,severe NPDR group,PDR group,and another 26 normal subjects( 52 eyes) were chosen as normal control group. All cases were examined by slit lamp microscope combined with supplementary lens,B ultrasound and optical coherence tomography,the posterior vitreous detachment( PVD) incidences were compared between different groups,the changes of vitreoretinal interface in patients with PDR before and after PRP in NPDR and PDR group were observed and compared. Results The PVD incidence in the severe NPDR group( 48. 3%) and the PDR group( 51. 7%) were obviously higher than that in the normal control( 7. 6%)( all P < 0. 01). The rates of patients with completely PVD in the severe NPDR group( 38. 3%) and the PDR group( 32. 8%) after PRP were higher than those before PRP( 16. 7% and 12. 1%)( P < 0. 01). Conclusion Abnormal vitreoretinal interface often concomitances with DR,PRP can induce the formation of entirely PVD to delay or prevent the pathological progression of DR and retinal detachment,which is able to improve the efficacy of vitreous operation.