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Issue:
The Expression of IL-1β in Gingiva of Adult Periodotitis Patients
Author(s):
YIN Lizuo
,
LIU Chunyi
,
HE Anguang
Pages:
25
-
26
Year:
2002
Issue:
1
Journal:
PROGRESS OF ANATOMICAL SCIENCES
Keyword:
成人牙周炎
;
白细胞介素-1β
;
细胞因子
;
Abstract:
目的探讨IL-1β在成人牙周炎性牙龈组织的分布及与炎症细胞浸润的关系.方法免疫组织化学SP方法.结果19例牙周炎组炎性牙龈标本中均有IL-1β蛋白阳性表达,阳性细胞数与正常对照组牙龈相比有非常显著差异(P<0.01).IL-1β阳性细胞主要为巨噬细胞.结论IL-1β可能参与了成人牙周炎的发生和发展.巨噬细胞是成人牙周炎炎性牙龈组织中表达细胞因子IL-1β的主要细胞类型,与成人牙周炎的发生和发展有关.
Citations
The gingival crevicular fluid interleukin-1 beta and tumour necrrosis factor-alpha levels in patients with rapidly progressive periodontitis
Yayuzyilmaz E
Australian Dental Jonrnal
Intedeukin-1β stimulates collagenase production by cultured human periodontal ligament fibroblasts
Ohshima M
Journal of Periodontal Research
Contribution of ILl beta to the enhancement of campylobac ter rectus lipopolysaccharied-stimulated PGE,production in old gingival fibroblasts in vitro
Takiguchi H
Mechanisms of Ageing and Development
Functional role of inter leukin 1 in periodontal disease:induction of interleukin 1 production by bacteroids gingivalis lipopolysaccharied in perionealmacrophages from C3H/HeN and C3H/HeJ mice
Hanazawa S
Infection and Immunity
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