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Mirabegron:a novel drug for overactive bladder symptom
Author(s): LI Hai-yuan, ZHOU Feng-hai, MA Yu-lei, LU Hai-di, The Second Clinical Medical College of Lanzhou University, Department of Urology, Lanzhou General Hospital of Lanzhou Command
Pages: 2215-
2218
Year: 2014
Issue:
19
Journal: Chinese Journal of New Drugs
Keyword: mirabegron; β 3 -adrenoceptor agonist; overactive bladder symptom; pharmacokinetics; clinical study;
Abstract: Mirabegron,a novel,potent and selective β3-adrenoceptor agonist,can increase bladder capacity,decrease the frequency of rhythmic bladder contractions,and prolong micturition interval.It can safely and effectively control the overactive bladder symptom.Clinical studies have confirmed that mirabegron can remarkably reduce the mean number of incontinence and micturitions per 24 h,increase the mean volume voided per micturition,and effectively improve urgency and nocturia episodes.With good safety and tolerability,mirabegron has become a novel treatment option for patients with overactive bladder symptom,improving their quality of life.
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