Author(s): Wang Xiao-song, Ouyang Qu-zhang, You County People’s Hospital, Hunan Province Tumor Hospital Central South University Xiangya Medicine School Cancer Center
Pages: 35-40
Year: 2014 Issue:  3
Journal: Journal of Hunan Normal University(Medical Science)
Keyword:  malignant tumor; breast cancer; survival analysis;
Abstract: Objective The overall survival( OS) analysis of 4720 cases female breast cancer in 1992—2005is performed in Hunan Province Tumor Hospital,which explores the factors affecting the survival of female breast cancer patients and provides the basis for the female breast cancer survival evaluation. Methods 4720 cases female breast cancer patients are taken respectively grouping antitheses according to their age,menstrual status,lymph node metastasis,receptor status,clinical stages,tumor location and sub-location,pathological type,therapies and so on,making use of statistical software spss18. 0 Kaplan-Meler method to calculate and observe the overall survival( OS) of each group and performs a statistical analysis. Results The overall survival( OS) of breast cancer 1,2,3,4,5,10,15 years was respectively 96,91,85,80,74,53 and 42,the overall survival( OS) of breast cancer patients is taken respectively grouping analysis with age,menopause,lymph node metastasis,estrogen receptor-positive or not,progesterone receptor-positive or not,CerbB-2-negative or not,clinical stage,whether invasive breast cancer or not,whether can take surgery,whether surgical cases for radical prostatectomy,whether the chemotherapy regimens containing anthracyclines and other aspects,whose differences were remarkable; while the parts or sub-parts that breast cancer occurs,infiltrative non-specific cancer were taken respectively grouping analysis,which has no significant differences. Conclusion Early detection,early diagnosis and early treatment of the breast cancer( surgery based) are still the key to improve the overall survival; immunohistochemistry state has a significant impact on the prognosis of female breast cancer.