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A new antidepressant,vortioxetine
Author(s): FAN Ning, YANG Fu-de, School of Psychology, Hebei United University, Beijing Huilongguan Hospital
Pages: 1847-
1850
Year: 2014
Issue:
16
Journal: Chinese Journal of New Drugs
Keyword: vortioxetine; 5-hydroxytryptamine reuptake inhibitor(SSRIs); depression; anxiety;
Abstract: Vortioxetine is a potent serotonin reuptake inhibitor and mainly used in the therapy of MDD in adults,and it was developed and commercialized by Lundbeck and Takeda Pharmaceutical company. Vortioxetine received its first approval for MDD by the US FDA in September 30,2013. A large number of clinical researches have confirmed that vortioxetine has good efficacy,safety and tolerability in the therapy of MDD. In this review,we summarized the mechanisms of antidepressant action,pharmacokinetic and pharmacodynamic studies,clinical trials and adverse effects of vortioxetine.
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