Effects of Lanzhou Prescription on Peripheral Blood Cells of the Mice with Aplastic Anemia
Author(s): ZHAN Rui, HUANG Bangrong, WANG Lanying, NI Hong, LIANG Xi, ZHANG Yongping
Pages: 10-12
Year: 2014 Issue: 9
Journal: Gansu Journal of Traditional Chinese Medicine
Keyword: aplastic anemia; peripheral blood cells; Lanzhou prescription; mice;
Abstract: Objective:To observe the influence and the mechanism of Lanzhou prescription on routine blood test and ganulophilocyte of the mice suffering from aplastic anemia (AA). Methods:Ninety BALB/C mice, body weight (20±2)g, were randomized into six groups:high, moderate and low dosage groups of Lanzhou prescriptions, the control group of ZhenQi FuZheng granules, the model group and normal control group, 15 mice each group. Ex-cept normal control group, 75 mice in other groups accepted whole-body exposure underγ-rays by 3.0GY linear ac-celerator, thymus and lymph nodes cell suspensions were drawn from DBA/2 mice and given to the mice by caudal vein after radiating in four hours. The models were successfully established by testing hemogram and myelogram. The changes of WBC, RBC, Hb and PLT in peripheral blood of the mice in different groups were observed in 20 and 40 days after treating. Results:Lanzhou prescription could obviously raise WBC, blood platelets and Hb in peripheral blood of AA mice, the difference had statistical meaning, the rise of RBC was insignificant. Conclusion: Lanzhou prescription could raise the amount of peripheral blood cells in AA mice, and it could cure AA to a certain degree.
Pages: 10-12
Year: 2014 Issue: 9
Journal: Gansu Journal of Traditional Chinese Medicine
Keyword: aplastic anemia; peripheral blood cells; Lanzhou prescription; mice;
Abstract: Objective:To observe the influence and the mechanism of Lanzhou prescription on routine blood test and ganulophilocyte of the mice suffering from aplastic anemia (AA). Methods:Ninety BALB/C mice, body weight (20±2)g, were randomized into six groups:high, moderate and low dosage groups of Lanzhou prescriptions, the control group of ZhenQi FuZheng granules, the model group and normal control group, 15 mice each group. Ex-cept normal control group, 75 mice in other groups accepted whole-body exposure underγ-rays by 3.0GY linear ac-celerator, thymus and lymph nodes cell suspensions were drawn from DBA/2 mice and given to the mice by caudal vein after radiating in four hours. The models were successfully established by testing hemogram and myelogram. The changes of WBC, RBC, Hb and PLT in peripheral blood of the mice in different groups were observed in 20 and 40 days after treating. Results:Lanzhou prescription could obviously raise WBC, blood platelets and Hb in peripheral blood of AA mice, the difference had statistical meaning, the rise of RBC was insignificant. Conclusion: Lanzhou prescription could raise the amount of peripheral blood cells in AA mice, and it could cure AA to a certain degree.
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