Effect of montelukast sodium combined with magnesium sulfate on elderly patients with bronchial asthma
Author(s): L IU Feng, ZHONG Li-qiu
Pages: 2705-2706,2709
Year: 2014 Issue: 19
Journal: Journal of Laboratory Medicine and Clinical Sciences
Keyword: bronchial asthma; montelukast sodium; magnesium sulfate; elderly patients;
Abstract: Objective To explore the clinical effect of montelukast sodium combined with magnesium sulfate on elderly patents with bronchial asthma .Methods Eighty elderly patients with bronchial asthma from June 2012 to June 2013 were divided into observation group and control group randomly ,each group were 40 patients .Patients in the control group were given conventional treatment such as oxygen uptake ,anti-infection ,expectorant ,B2 receptor agonist ,glucocorticoid .The observation group was added montelukast sodium chewable tablet combined with magne-sium sulfate injection on the basis of the conventional treatment .Results The total effective rate of the observation group(95 .0% ) was significant higher than that of the control group (75 .0% ) ,the recurrence rate of the observation group (7 .5% ) was significant lower than that of the control group (30 .0% ) (P< 0 .05) .The symptoms such as gasp ,cough and chest congestion of patients in the observation group relieved significant earlier than those of the con-trol group (P<0 .05) .Before treatment ,the lung function index of the two groups had no significant difference (P>0 .05) ,Lung function index of the two groups after treatment were significantly improved ,and that in the observation group was significant better than that in the control group (P< 0 .05);There were no respiratory depression ,de-creased blood pressure and other serious adverse reactions occurred in the two groups .Conclusion The effect of montelukast sodium combined with magnesium sulfate on the elderly patients with bronchial asthma was outstand-ing ,symptom relieved quickly ,recurrence rate was low ,which was safe and reliable ,worthy of clinical promotion .
Pages: 2705-2706,2709
Year: 2014 Issue: 19
Journal: Journal of Laboratory Medicine and Clinical Sciences
Keyword: bronchial asthma; montelukast sodium; magnesium sulfate; elderly patients;
Abstract: Objective To explore the clinical effect of montelukast sodium combined with magnesium sulfate on elderly patents with bronchial asthma .Methods Eighty elderly patients with bronchial asthma from June 2012 to June 2013 were divided into observation group and control group randomly ,each group were 40 patients .Patients in the control group were given conventional treatment such as oxygen uptake ,anti-infection ,expectorant ,B2 receptor agonist ,glucocorticoid .The observation group was added montelukast sodium chewable tablet combined with magne-sium sulfate injection on the basis of the conventional treatment .Results The total effective rate of the observation group(95 .0% ) was significant higher than that of the control group (75 .0% ) ,the recurrence rate of the observation group (7 .5% ) was significant lower than that of the control group (30 .0% ) (P< 0 .05) .The symptoms such as gasp ,cough and chest congestion of patients in the observation group relieved significant earlier than those of the con-trol group (P<0 .05) .Before treatment ,the lung function index of the two groups had no significant difference (P>0 .05) ,Lung function index of the two groups after treatment were significantly improved ,and that in the observation group was significant better than that in the control group (P< 0 .05);There were no respiratory depression ,de-creased blood pressure and other serious adverse reactions occurred in the two groups .Conclusion The effect of montelukast sodium combined with magnesium sulfate on the elderly patients with bronchial asthma was outstand-ing ,symptom relieved quickly ,recurrence rate was low ,which was safe and reliable ,worthy of clinical promotion .
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