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Analysis of Biochemical Markers in Serum of Guinea Pigs after Death Caused by Hypothermia
Author(s): LI Shi-ying, DENG Kai-fei, SHAO Yu, LI Zheng-dong, QIN Zhi-qiang, CHEN Yi-jiu, HUANG Ping
Pages: 241-
244
Year: 2014
Issue:
4
Journal: Journal of Forensic Medicine
Keyword: forensic pathology; hypothermia; serum; biochemical markers; guinea pigs;
Abstract: 目的 检测低温死亡豚鼠的血清生化指标的变化情况,并分析其变化规律,为利用生化指标推断低温死亡提供一定的参考.方法 20只豚鼠随机分为实验组和对照组,实验组置于-30C左右环境下至死亡,对照组置于25 C左右环境下,经相应时间后再断颈处死.分别提取右心血血清,使用生化仪对一系列血清生化指标进行检测.结果 相较于对照组,低温死亡豚鼠血清中葡萄糖、尿酸、肌酐及尿素氮含量升高(P<0.05),总蛋白和白蛋白含量降低(P<0.05),而其他指标如血清酶和血清离子等则无明显变化.结论 低温死亡下的血清生化指标的变化存在一定的特征性,有望在低温死亡原因推断中起到辅助鉴定作用.
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