Targeted Therapy and Chemotherapy for Triple-negative Breast Cancer
Author(s): HAN Yan-ze, ZHAO Jin-peng, SUN Yan-yan, Department of general surgery, The Fourth Affiliated Hospital of Harbin Medical University
Pages: 4397-4400
Year: 2014 Issue: 22
Journal: Biomagnetism
Keyword: Breast Cancer; Triple-negative; Chemotherapy; Targeted therapy;
Abstract: Triple negative breast cancer(TNBC) accounts for approxim ately 15% of breast cancer cases. TNBC is an immunohistochemically defined subtype, with significant diversity within the subtype. Generally TNBC occurs in younger women and is marked by high rates of relapse, visceral and CNS metastases, and early death. For the majority of TNBC patients, conventional chemotherapy is the main treatment method. 20% patients had good sensitivity to chemotherapy, chemotherapy resistance of patients with TNBC targeting therapy is the focus of current research, looking for new breast cancer therapeutic target, put forward TNBC of new therapeutic strategies, is expected to improve the prognosis of the patients with TNBC.
Pages: 4397-4400
Year: 2014 Issue: 22
Journal: Biomagnetism
Keyword: Breast Cancer; Triple-negative; Chemotherapy; Targeted therapy;
Abstract: Triple negative breast cancer(TNBC) accounts for approxim ately 15% of breast cancer cases. TNBC is an immunohistochemically defined subtype, with significant diversity within the subtype. Generally TNBC occurs in younger women and is marked by high rates of relapse, visceral and CNS metastases, and early death. For the majority of TNBC patients, conventional chemotherapy is the main treatment method. 20% patients had good sensitivity to chemotherapy, chemotherapy resistance of patients with TNBC targeting therapy is the focus of current research, looking for new breast cancer therapeutic target, put forward TNBC of new therapeutic strategies, is expected to improve the prognosis of the patients with TNBC.
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