Observation on Feiwei Medicinal Instant Granules on Pulmonary Interstitial Fibrosis and Its Effect on Tumor Markers of CA19-9
Author(s): Li Ying, Zhang Shunan
Pages: 990-993
Year: 2014 Issue: 8
Journal: World Chinese Medicine
Keyword: Pulmonary interstitial fibrosis; Benefiting vital energy and activating blood circulation; Feiwei medicinal instant granules; Clinical curative effect; Tumor markers of CA19-9;
Abstract: Objective:To observe the curative effect of the Feiwei medicinal instant granules on pulmonary interstitial fibrosis and effect on tumor markers of CA19-9.Methods:One hundred and twenty patients with pulmonary interstitial fibrosis were randomly divided into treatment group (n=61)and control group (n=59),and all of them were given fundamental treatment.Patients in the treatment group also received oral administration of Feiwei medicinal instant granules for consumptive lung disease twice a day,100ml a time.Patients in the control group were given oral administration of prednisone once a day,30mg each time.After 2 months of treatment,a series of chan-ges of the two groups before and after the treatment,including:TCM score,dyspnea scores,six-minutes walking test,TLC,FVC,FEV1 , FEV1/FVC,DLCO and tumor markers of CA19-9 were observed.Results:The total effective rates of TCMsyndrome in treatment group and control group were respectively 61.7% and 34.8%,and there was significant difference between the two groups.In the treatment group,TCM score,dyspnea scores,six-minutes walking test,TLC,FEV1 ,and tumor markers of CA19 -9 were improved obviously(P<0.05 or P<0.01).In the control group,the part of TCMscore,dyspnea scores were relatively improved,too(P<0.05).However,the treatment group was superior to control group in the improvement of TCM syndromes,dyspnea scores,six-minutes walking test,FVC and tumor markers of CA19-9.Conclusion:Feiwei medicinal instant granules can effectively relieve the symptoms of dyspnea in patients with pulmonary interstitial fibrosis,increase exercise tolerance,enhance the TLC,FEV1 in lung function,and bring patients more satisfac-tion.The medicinal instant granules may inhibit apoptosis of epithelial cells of IPF and abnormal proliferation.
Pages: 990-993
Year: 2014 Issue: 8
Journal: World Chinese Medicine
Keyword: Pulmonary interstitial fibrosis; Benefiting vital energy and activating blood circulation; Feiwei medicinal instant granules; Clinical curative effect; Tumor markers of CA19-9;
Abstract: Objective:To observe the curative effect of the Feiwei medicinal instant granules on pulmonary interstitial fibrosis and effect on tumor markers of CA19-9.Methods:One hundred and twenty patients with pulmonary interstitial fibrosis were randomly divided into treatment group (n=61)and control group (n=59),and all of them were given fundamental treatment.Patients in the treatment group also received oral administration of Feiwei medicinal instant granules for consumptive lung disease twice a day,100ml a time.Patients in the control group were given oral administration of prednisone once a day,30mg each time.After 2 months of treatment,a series of chan-ges of the two groups before and after the treatment,including:TCM score,dyspnea scores,six-minutes walking test,TLC,FVC,FEV1 , FEV1/FVC,DLCO and tumor markers of CA19-9 were observed.Results:The total effective rates of TCMsyndrome in treatment group and control group were respectively 61.7% and 34.8%,and there was significant difference between the two groups.In the treatment group,TCM score,dyspnea scores,six-minutes walking test,TLC,FEV1 ,and tumor markers of CA19 -9 were improved obviously(P<0.05 or P<0.01).In the control group,the part of TCMscore,dyspnea scores were relatively improved,too(P<0.05).However,the treatment group was superior to control group in the improvement of TCM syndromes,dyspnea scores,six-minutes walking test,FVC and tumor markers of CA19-9.Conclusion:Feiwei medicinal instant granules can effectively relieve the symptoms of dyspnea in patients with pulmonary interstitial fibrosis,increase exercise tolerance,enhance the TLC,FEV1 in lung function,and bring patients more satisfac-tion.The medicinal instant granules may inhibit apoptosis of epithelial cells of IPF and abnormal proliferation.
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