Clinical observation of the effects of remifentanil on draw reaction at cervical plexus anesthesia for thyroid operation
Author(s): XIA Shujiang, ZHANG Qingmei, GUO Chunnian, XIA Xiaoqiong
Pages: 910-912,913
Year: 2014 Issue: 7
Journal: Anhui Medical Journal
Keyword: Remifentanil; Droperidol/Dolantin; Nerve blockade; Thyroid;
Abstract: Objective To observe the effects of remifentanil on draw reaction at cervical plexus anesthesia for thyroid operation. Methods 60 cases of elective thyroid operation,ASAⅠ-Ⅱ,were randomly divided into three groups (group A,b and C,20 cases each).In group A,remifentanil 0.05 ~0.08 μg/kg was injected over 1 min and infused at a rate of 0.05 μg·kg-1 ·min-1 after skin incision.In group B,dolantin 50 mg and droperidol 2.5 mg were administered when disinfecting skin,and then 0.05 μg·kg-1 ·min-1 remifentanil was used by continual pump infusion since separated the cervical white line.While patients in group C received dolantin 1 mg/kg and droperidol 0.05 mg/kg when disinfecting skin,and superaddition of dolantin or fentanil in the event of a serious draw reaction.Adjusted injection rate of remifentanil according to the situations during operation,and stopped injecting before skin suture.Results In group C,the blood pressure and the heart rate increased significantly after surgery,especially when separating the thyroid gland(P<0.05).Patients in group A and B have a significantly lower increasing amplitude of BP and HR than that in group C after surgery or when pulling the thyroid gland(P<0.05 ).Pa-tients in group C had obvious pain aggravated when pulling the thyroid gland or its upper pole,which could not be suppressed by increasing the analgesic.while the pain was dramatically sighter and repressible in group A and B(P<0.05).At the end of the surgery,patients in group A had a lower Ramsay score and a higher VPS score is higher than those in groups B and C(P<0.05 ).Conclusion Continuous infusion with small dose of remifentanil can inhibit draw reaction in thyroid surgery under cervical plexus block anesthesia.If combined with a small dose of dolantin and droperidol,the dose of remifentanil should be reduced considerably,which would be safer and more effective.
Pages: 910-912,913
Year: 2014 Issue: 7
Journal: Anhui Medical Journal
Keyword: Remifentanil; Droperidol/Dolantin; Nerve blockade; Thyroid;
Abstract: Objective To observe the effects of remifentanil on draw reaction at cervical plexus anesthesia for thyroid operation. Methods 60 cases of elective thyroid operation,ASAⅠ-Ⅱ,were randomly divided into three groups (group A,b and C,20 cases each).In group A,remifentanil 0.05 ~0.08 μg/kg was injected over 1 min and infused at a rate of 0.05 μg·kg-1 ·min-1 after skin incision.In group B,dolantin 50 mg and droperidol 2.5 mg were administered when disinfecting skin,and then 0.05 μg·kg-1 ·min-1 remifentanil was used by continual pump infusion since separated the cervical white line.While patients in group C received dolantin 1 mg/kg and droperidol 0.05 mg/kg when disinfecting skin,and superaddition of dolantin or fentanil in the event of a serious draw reaction.Adjusted injection rate of remifentanil according to the situations during operation,and stopped injecting before skin suture.Results In group C,the blood pressure and the heart rate increased significantly after surgery,especially when separating the thyroid gland(P<0.05).Patients in group A and B have a significantly lower increasing amplitude of BP and HR than that in group C after surgery or when pulling the thyroid gland(P<0.05 ).Pa-tients in group C had obvious pain aggravated when pulling the thyroid gland or its upper pole,which could not be suppressed by increasing the analgesic.while the pain was dramatically sighter and repressible in group A and B(P<0.05).At the end of the surgery,patients in group A had a lower Ramsay score and a higher VPS score is higher than those in groups B and C(P<0.05 ).Conclusion Continuous infusion with small dose of remifentanil can inhibit draw reaction in thyroid surgery under cervical plexus block anesthesia.If combined with a small dose of dolantin and droperidol,the dose of remifentanil should be reduced considerably,which would be safer and more effective.
Related Articles