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Changes of Oscillatory Potentials of Electroretinogram after Methanol Intoxication in Rats
Author(s): LIU Dong-mei, ZHOU Shu, CHEN Jie-min, PENG Shu-ya, XIA Wen-tao
Pages: 178-
180
Year: 2014
Issue:
3
Journal: Journal of Forensic Medicine
Keyword: forensic medicine; poisoning; methanol; electroretinogram; oscillatory potentials; rats;
Abstract: Objective To study the characters of oscillatory potentials (OPs) of electroretinogram (ERG) after methanol intoxication in rats. Method The SD rat models of methanol intoxication were established and divided into control group, 3-day intoxication group, 7-day intoxication group. The changes of OPs of ERG were recorded in a dark room. Results The total amplitudes of 3-day and 7-day intoxication groups decreased approximately 50% compared with that of the control group, while the schedule de-layed approximately 16% and 61%, respectively. Conclusion The characters of methanol intoxication in rats included delay in schedule and decline in the total amplitude of OPs.
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