Author(s): ZOU Yun-zhi, WEN Ye-hua
Pages: 1636-1637
Year: 2014 Issue:  12
Journal: Journal of Laboratory Medicine and Clinical Sciences
Keyword:  vulvovaginal candidiasis; strain distribution; antimicrobial resistance;
Abstract: Objective To investigate distribution situation and its susceptibility of vulvovaginal candidiasis (VVC) pathogenic strains and its susceptibility ,to facilitate the effective treatment of the disease .Methods Test re-sults of pathogenicvaginal secretions of laboratory department in a hospital from 2010 to 2012 were retrospectively analyzed .Results From 2010 to 2012 ,the numbers of VVC-positive patients is 248 ,291 ,381 respectively which in-crease every year .The proportion of non-albicans in candidiasis were 11 .69% ,18 .21% and 24 .67% ,which increases every year ,the difference was statistically significant (P<0 .01) .Drug resistance rate of non-albicans to miconazole , itraconazole and other commonly usedantifungal drug is increased year by year ,to be exact ,from 6 .90% ,24 .14% up to 11 .89% ,37 .23% ,it is significantly different compared with the previous year (P<0 .05) .Conclusion The num-ber of VVC patients increased year by year .Over time ,VVC of pathogenic strains as well as resistance of pathogenic strains have changed to some extent ,in the course of VVC treatment should pay attention to the detection of patho-genic strains ,and a reasonable choice of antifungal agents should be based on susceptibility testing results to improve the cure rate of VVC .