Investigation and analysis of bacteria acute infection in severe burn wounds
Author(s): Yu Xiaofeng, Tao Renqing
Pages: 662-663,664
Year: 2014 Issue: 5
Journal: Anhui Medical Journal
Keyword: Wound sepsis; Dysbacteriosis; Imipenem; Vancomycin;
Abstract: Objective To understand the bacteria distribution in wound infection during acute infection period in severely burned pa-tients and provide laboratory basis for preventing and treating the invasive infection.Methods One hundred and sixty-three patients with TB-SA more than 3 1% and deep Пdegree and Ш degree of injury were investigated.The wound secretion was cultured and identified using VITEK2 automatic bacteria device in 13 to 15 d of acute infection period.Drug sensitive experiment was implemented and analysed according to the NCCLS.Results Twenty-four kinds of bacteria(163 strains)were harvested,and the positive rate was 100%,including false single spore fungus(33.1%)and staphylococcus aureus(22.7%).The imipenem,cefepime engine-grease,vancomycin and nitrofurantoin were used for 3 d.The wound sepsis in 163 patients was not found,and all patients were successfully cured.Conclusion The application of imipenem, cefepime engine-grease vancomycin and nitrofurantoincan can prevent the occurrence of wound sepsis and improve the clinical cure rate 13 to 15 d after severe burn injury.
Pages: 662-663,664
Year: 2014 Issue: 5
Journal: Anhui Medical Journal
Keyword: Wound sepsis; Dysbacteriosis; Imipenem; Vancomycin;
Abstract: Objective To understand the bacteria distribution in wound infection during acute infection period in severely burned pa-tients and provide laboratory basis for preventing and treating the invasive infection.Methods One hundred and sixty-three patients with TB-SA more than 3 1% and deep Пdegree and Ш degree of injury were investigated.The wound secretion was cultured and identified using VITEK2 automatic bacteria device in 13 to 15 d of acute infection period.Drug sensitive experiment was implemented and analysed according to the NCCLS.Results Twenty-four kinds of bacteria(163 strains)were harvested,and the positive rate was 100%,including false single spore fungus(33.1%)and staphylococcus aureus(22.7%).The imipenem,cefepime engine-grease,vancomycin and nitrofurantoin were used for 3 d.The wound sepsis in 163 patients was not found,and all patients were successfully cured.Conclusion The application of imipenem, cefepime engine-grease vancomycin and nitrofurantoincan can prevent the occurrence of wound sepsis and improve the clinical cure rate 13 to 15 d after severe burn injury.
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