Author(s): MING Di, HUANG Yun-li, GONG Li-hong, XU Xue, LI Hong-bin, Department of Dermatology, the First Affiliated Hospital of Kunming Medical University, Institute of Dermatology and Venereology of Yun-nan province
Pages: 1569-1571
Year: 2014 Issue:  8
Journal: Biomagnetism
Keyword:  Candida albicans; Genotyping; Antifungal drugs;
Abstract: Candida albicans colonization in the mouth of the majority of the population, under certain conditions, can become the dominant strains and lead to infection. In recent years,geno typing is a hot topic in molecular biology researching of albicans, with the development of science and technology, because of deep fungal infection ratio increases unceasingly, molecular biology method has been more and more widely used in clinical fungal disease research, so as to control albicans infection and provide a basis for the early diagnosis and treatment. This paper reviews theRFLP, RAPD, ITS regional sequence analysis of molecular biology technology in c. albicans genotyping related research, compared their advantages and disadvantages, and discuss the genotyped research applied to clinical diagnosis, treatment and the development of new antifungal development trend and board prospects. We believe that it is more useful to a variety of typing methods in combination, and with the aid of computer software to carry on the analysis, but it still need further investigation.