Recent progress in Vaspin as a novel adipokine
Author(s): LU Yu-yan, XU Ya-wei, Dept.of Cardiology, Tenth People’s Hospital, Tongji University
Pages: 116-120
Year: 2013 Issue: 5
Journal: Journal of Tongji University(Medical Science)
Keyword: Vaspin; adipokines; visceral obesity; obesity; diabetes mellitus; cardiovascular diseases;
Abstract: Visceral adipose tissue-derived serine protease inhibitor(Vaspin),has been recently identified as a novel adipokine with insulin-sensitizing effects,which is predominantly secreted from visceral adipose tissues.A number of studies have demonstrated that Vaspin level is associated with obesity,diabetes mellitus,cardiovascular diseases and so on.Vaspin not only promotes insulin sensitivity and glucose tolerance,but also inhibits vascular inflammation.These findings provide a new therapeutic direction of related diseases mentioned above.This paper is aimed to review the recent progress in Vaspin research.
Pages: 116-120
Year: 2013 Issue: 5
Journal: Journal of Tongji University(Medical Science)
Keyword: Vaspin; adipokines; visceral obesity; obesity; diabetes mellitus; cardiovascular diseases;
Abstract: Visceral adipose tissue-derived serine protease inhibitor(Vaspin),has been recently identified as a novel adipokine with insulin-sensitizing effects,which is predominantly secreted from visceral adipose tissues.A number of studies have demonstrated that Vaspin level is associated with obesity,diabetes mellitus,cardiovascular diseases and so on.Vaspin not only promotes insulin sensitivity and glucose tolerance,but also inhibits vascular inflammation.These findings provide a new therapeutic direction of related diseases mentioned above.This paper is aimed to review the recent progress in Vaspin research.
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