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Clinical Observation of “Guiyuan Formula”on Different-aged Patients of Decreasing Ovarian Store
Author(s): 
Pages: 35-39
Year: Issue:  6
Journal: Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai

Keyword:  Decreasing ovarian store(DOS)"Guiyuan Formula"ageclinical observation;
Abstract: Objective: To observe the clinical efficacy of "Guiyuan Formula"on different-aged patients of decreasing ovarian store( DOS). Methods: Sixty-four patients with DOS were selected,which were divided into Chinese medicine group( n =34) and western medicine group( n =30) with a non-randomized concurrent control trial. The Chinese medicine group was treated with"Guiyuan Formula",and the western medicine group was treated with hormone replacement therapy,with a course of 3 months. The serum sex hormone levels,the symptoms of traditional Chinese medicine( TCM),the menstrual cycle and the case of pregnancy were evaluated stratified by age. Results: Among the patients of more than 30 years old,after treatment,the level of FSH in Chinese medicine group was significantly decreased( P < 0. 05),the level of E 2 was obviously increased( P < 0. 05),and there was statistical difference between two groups in the difference-value of FSH between before and after treatment( P < 0. 01). Among the patients of more than 30 years old,the total effective rates of Chinese medicine group and western medicine group were 80. 00% and 42. 85% respectively on TCM syndrome,and the effect of Chinese medicine group was better than western medicine group( P < 0. 05). Three months follow-up after treatment,the menstrual cycle of patients of less than 30 years old in western medicine group was remarkably improved( P < 0. 05),and the menstrual cycle of patients of more than 30 years old in Chinese medicine group was also improved( P < 0. 01). There was no statistical difference between two groups in the aspect of pregnancy( P > 0. 05). Conclusion: "Guiyuan Formula"can greatly improve the clinical symptoms,menstrual cycle and the levels of serum sex hormones of patients with DOS. Especially for the patients of more than 30 years old,"Guiyuan Formula"has more clinical advantages than the hormone replacement therapy.
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